关键词搜索: 3D细胞培养相关产品,多肽毒素,原代细胞,细胞因子,抗体,试剂盒,各类细菌、病毒荧光定量PCR试剂盒,转基因检测仪器和耗材等。

你的位置:首页 > 产品展示 > > 离子通道研究用多肽毒素 >Phrixotoxin-2 / PaTx2

产品详细页

Phrixotoxin-2 / PaTx2

简要描述:Smartox Biotechnology是*一家专门生产动物毒液多肽毒素,用于细胞离子通道功能研究的生物医药公司。多肽毒素在生物制药领域具有重要的使用价值。

  • 产品型号:PHX002-50010
  • 厂商性质:代理商
  • 更新时间:2017-09-30
  • 访  问  量:1093

产品介绍

Phrixotoxin-2 / PaTx2 

 

Blocker of Kv4.2 and Kv4.3 channels(钾离子通道Kv4.2 Kv4.3阻断剂)

 

Phrixotoxin-2 (PaTx2) has been isolated originally from the venom of the Chile fire tarantula Phrixotrichus auratus. Phrixotoxin-2 is a 31 amino acid peptide that contains three disulphide bridges. Phrixotoxin-2 specifically blocks recombinant Kv4.2 and Kv4.3 currents with IC50 values of 34 nM and 71 nM, respectively. It does so by altering the gating properties of the channels. The inhibition of Kv4.2 and Kv4.3 currents is fully reversible upon washout. Kv4.1 is only slightly sensitive to Phrixotoxin-2 (maximal block of 20 by 300 nM). Kv1, Kv2 and Kv3 channel subfamilies are insensitive to this toxin.

 

Phrixotoxin-2 技术资料

氨基酸序列:Tyr-Cys2-Gln-Lys-Trp-Met-Trp-Thr-Cys9-Asp-Glu-Glu-Arg-Lys-Cys15-Cys16-Glu-Gly-Leu-Val-Cys21-Arg-Leu-Trp-Cys25-Lys-Arg-Ile-Ile-Asn-Met-NH2 

二硫键:Cys2-Cys16, Cys9-Cys21 and Cys15-Cys25 

长度 (aa) 31

分子式: C169H259N49O43S8 

分子量:  3921.71 Da

外观:white lyophilized solid

可溶性:water or saline buffer

CAS 号:221889-63-0 

来源:Synthetic

纯度:> 98%

 

产品信息

PHX002-50010

Phrixotoxin-2

      5 x 0.01mg

PHX002-00100

Phrixotoxin-2

0.1mg

PHX002-00500

Phrixotoxin-2

0.5mg

PHX002-01000

Phrixotoxin-2

1mg

 

留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
在线咨询
电话咨询
13581534696
关注微信