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抗dsRNA单克隆抗体—K2抗体

简要描述:北京群晓科苑生物技术有限公司代理匈牙利SCICONS公司产品。SCICONS公司的主推产品是抗dsRNA单克隆抗体,如K1单克隆抗体、K2单克隆抗体和J2单克隆抗体。

  • 产品型号:K2-0801
  • 厂商性质:代理商
  • 更新时间:2019-09-30
  • 访  问  量:862

产品介绍

Antibodies - K2

K2单克隆抗体—抗dsRNA抗体


 

K2单克隆抗体,lgM亚型,是抗dsRNA的单克隆抗体。


 

K2抗体主要用于一些特殊的检测。K2抗体主要用于ELISA和夹心法ELISA实验,一般来说,K2抗体只能用于检测IgG(IgG2a)亚型抗体不适合的双链RNA(dsRNA)。


 

K2抗体需干冰运输,因为高浓度的K2抗体容易发生凝聚,因为不容易做成冻干粉,不能常温运输。


 


K2 anti-dsRNA monoclonal antibody has an IgM isotype.


 

K2 is mainly used for specialised applications, where J2 and K1 - antibodies that can be shipped at ambient temperature - do not suffice. Due to its IgM isotype K2 is more prone to aggregation at high concentration, and therefore cannot be lyophilised and needs to be shipped on ice.


 

K2 has primarily been used in ELISA and sandwich ELISA. Generally, K2 can be used in applications where an anti-dsRNA antibody with an isotype other than IgG (IgG2a) is required.


 

参考文献

Sch?nborn, J., Oberstrass, J., Breyel, E., Tittgen, J., Schumacher, J. and Lukacs, N. (1991) Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extracts. Nucleic Acids Res.19, 2993-3000.


 

Lukacs, N. (1994) Detection of virus infection in plants and differentiation between coexisting viruses by monoclonal antibodies to double-stranded RNA. J. Virol. Methods 47, 255-272.


 

Lukacs, N. (1997) Detection of sense:antisense duplexes by structure-specific anti-RNA antibodies. In: Antisense Technology. A Practical Approach, C. Lichtenstein and W. Nellen (eds), pp. 281-295. IRL Press, Oxford.

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