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产品介绍
Maurocalcine
Agonist of ryanodine receptors(鱼尼丁受体激动剂)
Maurocalcine, a component of the venom of Scorpio maurus palmatus, was discovered by Michel De Waard, co-founder of Smartox. folds according to an inhibitor cysteine knot. Such as Imperatoxin A, acts as a high affinity agonist of the type-1 ryanodine receptorexpressed in skeletal muscles with an affinity in the 10 nM range. induces an increase in channel opening probability accompanied by sudden transitions to long lasting subconductance states. has also been characterized as a cell penetrating peptide and its pharmacological activity can be observed upon extracellular perfusion.
技术资料
氨基酸序列:
Gly-Asp-Cys3-Leu-Pro-His-Leu-Lys-Leu-Cys10-Lys-Glu-Asn-Lys-Asp-Cys16-Cys17-Ser-Lys-Lys-Cys21-Lys-Arg-Arg-Gly-Thr-Asn-Ile-Glu-Lys-Arg-Cys32-Arg-OH
二硫键: Cys3-Cys17, Cys10-Cys21 and Cys16-Cys32
长度 (aa):33
分子式: C156H260N56O46S 6
分子量: 3858.8 Da
外观: White lyophilized solid
可溶性: water and saline buffer
CAS 号:not available
来源:Synthetic
纯度: > 98 %
产品信息
07MAU001-00100 | 0.1mg | |
07MAU001-00500 | 0.5mg | |
07MAU001-01000 | 1mg |